Summary of passive and active membrane properties recorded in the current-clamp mode at a membrane potential of -60 mV during baseline and in presence of DynA (n = 14).
Baseline
DynA
Mean
SEM
Mean
SEM
p-value
Rin [MΩ]
629
51
431
43
0.01
Tau [ms]
38.2
1.9
32.7
3.3
0.17
Threshold [mV]
-41.2
0.6
-38.9
1.0
0.06
AP amplitude [mV]
73.7
0.7
68.4
0.9
0.03
AHP [mV]
17.6
0.6
18.8
0.5
0.15
Half-width [ms]
1.2
0.1
1.1
0.1
0.31
slAHP [mV]
3.1
0.5
1.4
0.3
0.01
Amplitudelast [mV]
53.7
2.2
53.3
2.8
0.92
AHPlast [mV]
17.0
0.9
18.8
0.7
0.13
Inst. frequency [Hz]
34.8
1.7
28.7
2.5
0.06
Time to 1st AP [ms]
12.2
0.8
14.0
1.3
0.25
Significant changes are marked in bold. Differences with a strong trend, but not reaching the p < 0.05 significance criteria are marked in italic.